Gene transcriptions/Proximal promoters

< Gene transcriptions

"[T]he proximal sequence upstream of the gene that tends to contain primary regulatory elements" is a proximal promoter.[1]

It is "[a]pproximately 250 base pairs [or nucleotides, nts] upstream of the [transcription] start site".[1]

Genetics

Def. "[a] unit of heredity; a segment of DNA or RNA that is transmitted from one generation to the next, and that carries genetic information such as the sequence of amino acids for a protein"[2] is called a gene.

"The genetic information in a genome is held within genes, and the complete set of this information in an organism is called its genotype. A gene is a unit of heredity and is a region of DNA that influences a particular characteristic in an organism. Genes contain an open reading frame that can be transcribed, as well as regulatory sequences such as promoters and enhancers, which control the transcription of the open reading frame."[3]

Promoters

Def. a "section of DNA that controls the initiation of RNA transcription as a product of a gene"[4] is called a promoter.

Proximus

Def. "neighbour, nearest person or thing"[5] is called proximus.

Distal promoters

A distal promoter is a distant (in numbers of nucleotides) portion of the promoter for a particular gene.

This distal sequence is upstream of the gene.

It is a region of DNA that may contain additional regulatory elements, often with a weaker influence than the proximal promoter.

Dispersed promoters

Focused promoters

Intermediate promoters

Original research

Hypothesis:

  1. At least one promoter occurs within the proximal promoter of A1BG.

See also

References

  1. 1 2 "Promoter (genetics), In: Wikipedia". San Francisco, California: Wikimedia Foundation, Inc. June 14, 2013. Retrieved 2013-06-15.
  2. ↑ "gene, In: Wiktionary". San Francisco, California: Wikimedia Foundation, Inc. December 13, 2012. Retrieved 2012-12-13.
  3. ↑ "DNA, In: Wikipedia". San Francisco, California: Wikimedia Foundation, Inc. December 4, 2012. Retrieved 2012-12-13.
  4. ↑ "promoter, In: Wiktionary". San Francisco, California: Wikimedia Foundation, Inc. 28 May 2014. Retrieved 2014-06-08.
  5. ↑ "proximus, In: Wiktionary". San Francisco, California: Wikimedia Foundation, Inc. 17 April 2014. Retrieved 2014-06-08.

External links

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