HLA/DRB1*14:54

Ethnic Origin


Linkage Disequilibrium

DRB1 DRB345 DQA1 DQB1 NegLogFreq Notes
DRB1*14:54 DRB3*02:02:01 DQA1*01:04:01 DQB1*05:03:01 1.6 Universal
DRB1*14:54 DRB3*02:02:01 DQA1*01:04:01 DQB1*05:02:01 3.2 Asian
DRB1*14:54 DRB3*02:02:01 DQA1*01:04:01 DQB1*06:02:01 3.5
DRB1*14:54 DRB3*02:02:01 DQA1*01:04:01 DQB1*05:01:01 3.5
DRB1*14:54 DRB3*02:03 DQA1*01:04:01 DQB1*05:03:01 4

IMGT

IMGT

Typing problems

Most of the allele assignments of DRB1*14:01:01 prior to 2008 were actually DRB1*14:54 instead of DRB1*14:01:01. About 95% of them are DRB1*14:54 and only about 5% are DRB1*14:01:01. The difference between the two alleles is in exon 3, which is typically not analysed. The association with DRB3 can be used to tell the difference in the great majority of cases.


This article is issued from Wikiversity - version of the Saturday, January 22, 2011. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.