Gene transcriptions/Start sites/Quiz

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This is an image of Bob, the guinea pig. Credit: selbst.

Transcription start site is a lecture and an article as part of the gene transcription series.

You are free to take this quiz based on the transcription start site at any time.

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Quiz

Point added for a correct answer:   
Points for a wrong answer:
Ignore the questions' coefficients:

1. The portion of a promoter in which a transcription start site is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
enhancer
focused promoter
core promoter

2. Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

3. True or False, Some transcription start sites are located in the dispersed promoter.

TRUE
FALSE

4. Which of the following is not a transcriptional characteristic of transcription start sites?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
G/A/T-G/C+1-G-T/C-G-G-G/A-A-G/C
in eukaryotes
TATA-less genes
a consensus sequence

5. Complete the text:

The transcription start site is the where transcription at the -end of a sequence.

6. Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter .
includes the transcription start site .
proximal promoter .
distal promoter .
core promoter
usually 25 nucleotides upstream .

7. Which of the following are phenomena associated with transcription start sites?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
core promoter

8. True or False, Transcription start sites are found in the promoter regions of at least 1% of human genes.

TRUE
FALSE

Your score is 0 / 0

Research

Hypothesis:

  1. A1BG may have up to four transcription start sites.

Control groups

This is an image of a Lewis rat. Credit: Charles River Laboratories.

The findings demonstrate a statistically systematic change from the status quo or the control group.

“In the design of experiments, treatments [or special properties or characteristics] are applied to [or observed in] experimental units in the treatment group(s).[1] In comparative experiments, members of the complementary group, the control group, receive either no treatment or a standard treatment.[2]"[3]

Proof of concept

Def. a “short and/or incomplete realization of a certain method or idea to demonstrate its feasibility"[4] is called a proof of concept.

Def. evidence that demonstrates that a concept is possible is called proof of concept.

The proof-of-concept structure consists of

  1. background,
  2. procedures,
  3. findings, and
  4. interpretation.[5]

See also

References

  1. ↑ Klaus Hinkelmann, Oscar Kempthorne (2008). Design and Analysis of Experiments, Volume I: Introduction to Experimental Design (2nd ed.). Wiley. ISBN 978-0-471-72756-9. http://books.google.com/?id=T3wWj2kVYZgC&printsec=frontcover.
  2. ↑ R. A. Bailey (2008). Design of comparative experiments. Cambridge University Press. ISBN 978-0-521-68357-9. http://www.cambridge.org/uk/catalogue/catalogue.asp?isbn=9780521683579.
  3. ↑ "Treatment and control groups, In: Wikipedia". San Francisco, California: Wikimedia Foundation, Inc. May 18, 2012. Retrieved 2012-05-31.
  4. ↑ "proof of concept, In: Wiktionary". San Francisco, California: Wikimedia Foundation, Inc. November 10, 2012. Retrieved 2013-01-13.
  5. ↑ Ginger Lehrman and Ian B Hogue, Sarah Palmer, Cheryl Jennings, Celsa A Spina, Ann Wiegand, Alan L Landay, Robert W Coombs, Douglas D Richman, John W Mellors, John M Coffin, Ronald J Bosch, David M Margolis (August 13, 2005). "Depletion of latent HIV-1 infection in vivo: a proof-of-concept study". Lancet 366 (9485): 549-55. doi:10.1016/S0140-6736(05)67098-5. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894952/. Retrieved 2012-05-09.

External links

This is a research project at http://en.wikiversity.org

Development status: this resource is experimental in nature.
Educational level: this is a research resource.
Resource type: this resource is a quiz.
Subject classification: this is a genetics resource.
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