Gene transcriptions/Course

< Gene transcriptions

This course in gene transcription is dynamic only.

The course is built upon the ongoing research performed by geneticists around the world and here at Wikiversity.

In line with the Wikiversity ideal of learning by doing are a number of quizzes.

In some instances your interactions and responses may be used for research purposes, such as improving the quizzes. Your username and/or other identifiers are not included. If the resource itself is also being used for research purposes you will see the icon: . If your actions have been used for research purposes, this little icon may appear on your user talk page.

The general subject area is genetics. This includes knowledge of physics, chemistry, geography, history, and other subjects.

Prerequisites

Although an introduction to biochemistry would be a good idea, it is not required. Most of the information is descriptive.

If the freedom to write and execute computer programs online here at Wikiversity becomes available, you may be able to submit small programs to scan sections of DNA.


Completion levels

This course is dynamic only, which means lectures and other course resources may change without notice. If you work through all the quizzes and read or reinforce the lecture information in your mind, you may want to stop back after a year and perhaps learn more.

Lectures and quizzes may have a level of completion icon following them based on ≥ 100 kb equals 100 %, or 100 questions is 100 %, the midterm and final are based on 300 questions equals 100 %:

  1. This resource is a stub, which means that pretty well nothing has been done yet. 0-5%.
  2. This resource is just getting off the ground. Please feel welcome to help! 6-15%.
  3. Been started, but most of the work is still to be done - 16-30%.
  4. About halfway there. You may help to clarify and expand it - 31-45%.
  5. Almost complete, but you can help make it more thorough - 46-60%.
  6. Ready for testing by learners and teachers. Please begin! 61-75%.
  7. This resource is considered to be ready for use - 76-90%. R
  8. This resource has reached a high level of completion - 91-100%. C

A completion icon may not be present for all resources.

Lectures

Each lecture has or will have an associated quiz. Lectures are arranged in alphabetical order but can be enjoyed in any order.

Some of the lectures appear as red links until the older version is moved to the new title. Check the gene project template for the older title.

Red link lectures are just waiting for you to create. Be bold and proactive.

Lecture titles that are not yet plural need to be moved to a new title that is plural.

Each lecture appears more enticing with an image at the top.

  1. AGC boxes
  2. Angiotensinogen core promoter element
  3. Assembly of the transcription preinitiation complex
  4. ATA boxes
  5. Autonomously replicating sequences
  6. Boxes
  7. B recognition element
  8. CAAT boxes
  9. CArG boxes
  10. C/D boxes
  11. CENP-B boxes
  12. CGCG boxes
  13. Chromatins
  14. Chromoboxes
  15. Coactivators
  16. Corepressors
  17. Consensus sequences
  18. Core promoters
  19. Deoxyribonucleic acids
  20. Dispersed promoters
  21. Distal promoters
  22. DNA melting
  23. Downregulations
  24. Downstream core element
  25. Downstream promoter element
  26. Downstream TFIIB recognition element
  27. E2 boxes
  28. EIF4E basal element
  29. Enhancer boxes
  30. Enhancers
  31. Epigenomes
  32. Eukaryotic initiation factors
  33. F boxes
  34. Focused promoters
  35. Forkhead boxes
  36. Fur boxes
  37. GAAC elements
  38. G boxes
  39. GC boxes
  40. GCC boxes
  41. Gene transcriptions/Promoters
  42. General transcription factor II A
  43. General transcription factor II B
  44. General transcription factor II D
  45. General transcription factor II F
  46. General transcription factor II H
  47. General transcription factor II I
  48. Genes
  49. Gene transcriptions
  50. Histones
  51. HMG boxes
  52. HNG boxes
  53. Homeoboxes
  54. HY boxes
  55. Inhibitory peptides
  56. Initiator elements
  57. Insulators
  58. Intermediate promoters
  59. Isoforms
  60. MADS boxes
  61. Mediator complexes
  62. Metal responsive elements
  63. Motif ten elements
  64. Nucleosomes
  65. Operons
  66. P boxes
  67. Preinitiation complexes
  68. Pribnow boxes
  69. Proximal promoters
  70. Pseudogenes
  71. Regulons
  72. RNA polymerase I
  73. RNA polymerase II
  74. RNA polymerase II holoenzyme complexes
  75. RNA polymerase II holoenzymes
  76. RNA polymerase III
  77. RNA polymerases
  78. Stimulons
  79. TACTAAC boxes
  80. TATA binding protein associated factors
  81. TATA binding proteins
  82. TATA boxes
  83. Transcriptional regulations
  84. Transcription bubbles
  85. Transcription factories
  86. Gene transcriptions/Factors
  87. Transcription of A1BG
  88. Transcription start sites
  89. Upregulations
  90. Upstream and downstream
  91. X boxes
  92. X core promoter element 1
  93. Y boxes

Quizzes

The quizzes may be rated by number of questions, with 100 questions being a high level of completion, even though some are at lower numbers of questions.

Hourlies

If you're really feeling like you know this stuff, try one of our hourlies, so called because they take about an hour to work through.

Research

Hypothesis:

  1. Several courses could be offered dealing with aspects of genetics or gene transcription.

Control groups

This is an image of a Lewis rat. Credit: Charles River Laboratories.

The findings demonstrate a statistically systematic change from the status quo or the control group.

“In the design of experiments, treatments [or special properties or characteristics] are applied to [or observed in] experimental units in the treatment group(s).[1] In comparative experiments, members of the complementary group, the control group, receive either no treatment or a standard treatment.[2]"[3]

Proof of concept

Def. a “short and/or incomplete realization of a certain method or idea to demonstrate its feasibility"[4] is called a proof of concept.

Def. evidence that demonstrates that a concept is possible is called proof of concept.

The proof-of-concept structure consists of

  1. background,
  2. procedures,
  3. findings, and
  4. interpretation.[5]

See also

References

  1. ↑ Klaus Hinkelmann, Oscar Kempthorne (2008). Design and Analysis of Experiments, Volume I: Introduction to Experimental Design (2nd ed.). Wiley. ISBN 978-0-471-72756-9. http://books.google.com/?id=T3wWj2kVYZgC&printsec=frontcover.
  2. ↑ R. A. Bailey (2008). Design of comparative experiments. Cambridge University Press. ISBN 978-0-521-68357-9. http://www.cambridge.org/uk/catalogue/catalogue.asp?isbn=9780521683579.
  3. ↑ "Treatment and control groups, In: Wikipedia". San Francisco, California: Wikimedia Foundation, Inc. May 18, 2012. Retrieved 2012-05-31.
  4. ↑ "proof of concept, In: Wiktionary". San Francisco, California: Wikimedia Foundation, Inc. November 10, 2012. Retrieved 2013-01-13.
  5. ↑ Ginger Lehrman and Ian B Hogue, Sarah Palmer, Cheryl Jennings, Celsa A Spina, Ann Wiegand, Alan L Landay, Robert W Coombs, Douglas D Richman, John W Mellors, John M Coffin, Ronald J Bosch, David M Margolis (August 13, 2005). "Depletion of latent HIV-1 infection in vivo: a proof-of-concept study". Lancet 366 (9485): 549-55. doi:10.1016/S0140-6736(05)67098-5. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894952/. Retrieved 2012-05-09.

External links

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