Radiation Oncology/NHL/Cutaneous

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Cutaneous Lymphoma

WHO; 2008 PMID 15692063 -- "WHO-EORTC classification for cutaneous lymphomas." (Willemze R, Blood. 2005 May 15;105(10):3768-85.)
- Classification system for primary cutaneous lymphomas

Histology	Frequency	5-year DSS	Clinical Course
T-cell cutaneous lymphomas
Mycosis fungoides	44%	88%	Indolent
Variants of MF	<5%	80-100%	Indolent
Sezary syndrome	3%	24%	Aggressive
Primary cutaneous anaplastic large cell lymphoma (CD30+)	8%	95%	Indolent
Lymphomatoid papulosis (CD30+)	12%	100%	Indolent
Subcutaneous panniculitis-like T-cell lymphoma	1%	82%	Indolent
Extranodal NK/T-cell lymphoma, nasal type	<1%	--	Aggressive
Primary cutaneous T-cell lymphoma, unspecified	2%	16%	Aggressive
B-cell cutaneous lymphomas
Primary cutaneous marginal zone B-cell lymphoma	7%	99%	Indolent
Primary cutaneous follicle center lymphoma	11%	95%	Indolent
Primary cutaneous diffuse large B-cell lymphoma, leg type	4%	55%	Intermediate
Primary cutaneous diffuse large B-cell lymphoma, other	<1%	50%	Intermediate

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