Radiation Oncology/Cancer Syndromes/Ataxia-Telangiectasia-Like Disorder
< Radiation Oncology < Cancer Syndromes
|
Ataxia-Telangiectasia-Like Disorder
- Mutation in MRE11 (part of MRN complex)
- Critical in recognition and repair of DNA double strand breaks
- Cells are radiosensitive
- Similar clinical features as Ataxia-Telangiectasia
- Birmingham, UK; 2004 PMID 15279810 -- "Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis."(Taylor AM, DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1219-25.)
- Review
This article is issued from Wikibooks. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.