Radiation Oncology/CNS/Sphenopalatine neuralgia

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Sphenopalatine Neuralgia

Rare craniofacial pain syndrome, also known as Sluder's Neuralgia
Characterized by unilateral pain in the orbit, mouth, nose, and posterior mastoid process.
Also associated increased autonomic activity resulting in ipsilateral nasal drainage, eye irritation, and lacrimation
May be caused by irritation of the pterygopalatine ganglion, possibly secondary to infection
Typically female 2:1 male predominance

Pittsburgh; 1997 PMID 9285614 -- "Stereotactic radiosurgical treatment of sphenopalatine neuralgia. Case report." (Pollock BE, J Neurosurg. 1997 Sep;87(3):450-3.)
- Case report. SRS 45 Gy to 50% isodose line. Pain free x8 months
- Recurrence 50% pain at 17 months, retreated with 40 Gy to 50% isodose line, and pain-free at 7 month follow-up

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