Spinosad

Administration
  • Type: Pediculicide
  • Dosage Forms:
  • Routes of Administration: Topical
  • Common Trade Names: Natroba

Adult Dosing
  • Apply to dry hair/scalp, rinse after 10m

Pediatric Dosing
  • <6mo: do not use
  • >6mo: apply to dry hair/scalp, rinse after 10m

Special Populations

Pregnancy Rating
  • Pregnancy Category B

Lactation risk
  • Pump/dump for 8h due to risk of benzyl alcohol systemic absorption

Renal Dosing

    Hepatic Dosing

      Contraindications
      • Allergy to class/drug
      • Infants <6mo (contains benzyl alcohol which is harmful to infants if absorbed

      Adverse Reactions

      Serious


      Common
      • Application site erythema, irritation, dryness, exfoliation
      • Ocular erythema/hyperemia
      • Alopecia
      • Dry skin

      Pharmacology
      • Half-life:
      • Metabolism:
      • Excretion:

      Mechanism of Action
      • "Causes neuronal excitation in insects, followed by hyperexcitation, paralysis, and death" (!)[1]

      Comments


      See Also

      References
      1. https://reference.medscape.com/drug/natroba-spinosad-999619#10
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