P450
Background
Antimicrobials
Avoid /P450 Inhibitors
- Quinolones, especially levofloxacin
- Macrolides, especially erythromycin
- Bactrim and sulfonamides
- Flagyl
- Nafcillin, oxacillin
Use
- Azithromycin
- Gentamicin
- Cephalosporin, aminopenicillins
- Nitrofurantoin
- Clindamycin
- Vancomycin
Significant P450 Inhibitors in General
- Grapefruit juice
- Valproate]
- INH
- Protease inhibitors (-navir, i.e. ritonavir)
- SSRIs, except escitalopram
- Amiodarone
- Fluoroquinolones
- Sulfonamides
- Macrolides
- Cimetidine
- Omeprazole
- Ketoconazole
- Acute ETOH
Significant P450 Inducers in General
- Phenytoin
- Carbamazepine
- Ethosuximide
- Quinidine/quinine
- Rifampin
- Griseofulvin
- Glucocorticoids
- Barbiturates
- St. John's wort
- Chronic EtOH
- Tobacco smoking
This article is issued from
Wikem.
The text is licensed under Creative
Commons - Attribution - Sharealike.
Additional terms may apply for the media files.