Miconazole

Administration
  • Type: Antifungal
  • Dosage Forms: 2% Cream
  • Routes of Administration: Topical
  • Common Trade Names: Monistat-Derm, Desenex, Lotrimin, Micatin, Zeasorb

Adult Dosing

Candidiasis, cutaneous
  • Apply 2% Cream BID to affected area x2 weeks

Tinea corporis
  • Apply 2% Cream BID to affected area x4 weeks

Tinea cruris
  • Apply 2% Cream BID to affected area x2 weeks

Tinea pedis
  • Apply 2% Cream BID to affected area x4 weeks

Pediatric Dosing

Candidiasis, cutaneous
  • Apply 2% Cream BID to affected area x2 weeks

Tinea corporis
  • Apply 2% Cream BID to affected area x4 weeks

Tinea cruris
  • Apply 2% Cream BID to affected area x2 weeks

Tinea pedis
  • Apply 2% Cream BID to affected area x4 weeks

Special Populations

Pregnancy Rating
  • Risk of fetal harm no expected
  • May use during pregnancy

Lactation risk
  • May use while breastfeeding

Renal Dosing
  • Adult: Not defined
  • Pediatric: Not defined

Hepatic Dosing
  • Adult: Not defined
  • Pediatric: Not defined

Contraindications
  • Allergy to class/drug

Adverse Reactions

Serious
  • May occur, but none reported

Common

Pharmacology
  • Half-life: Unknown
  • Metabolism: None, minimal systemic absorption
  • Excretion: None

Mechanism of Action
  • Inhibits 14-alpha demethylase, reducing fungal cell membrane ergosterol synthesis

Comments


See Also


References
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