Fusobacterium necrophorum

Background

  • Anaerobic gram negative rods.
  • Head and neck infection (e.g. Lemierre's syndrome)
    • Associated with poor dentition and/or aspiration

Antibiotic Sensitivities[1]

Category Antibiotic Sensitivity
PenicillinsPenicillin GI
Penicillin VI
Anti-Staphylocccal PenicillinsMethicillinX1
Nafcillin/OxacillinX1
Cloxacillin/Diclox.X1
Amino-PenicillinsAMP/AmoxS
Amox-ClavS
AMP-SulbS
Anti-Pseudomonal PenicillinsTicarcillinX1
Ticar-ClavS
Pip-TazoS
PiperacillinX1
CarbapenemsDoripenemS
ErtapenemS
ImipenemS
MeropenemS
AztreonamX1
FluroquinolonesCiprofloxacinX1
OfloxacinX1
PefloxacinX1
LevofloxacinX1
MoxifloxacinI
GemifloxacinX1
GatifloxacinX1
1st G CephaloCefazolinX1
2nd G. CephaloCefotetanX1
CefoxitinS
CefuroximeX1
3rd/4th G. CephaloCefotaximeX1
CefizoximeX1
CefTRIAXoneX1
CeftarolineX1
CefTAZidimeX1
CefepimeX1
Oral 1st G. CephaloCefadroxilX1
CephalexinX1
Oral 2nd G. CephaloCefaclor/LoracarbefX1
CefproxilX1
Cefuroxime axetilX1
Oral 3rd G. CephaloCefiximeX1
CeftibutenX1
Cefpodox/Cefdinir/CefditorenX1
AminoglycosidesGentamicinR
TobramycinR
AmikacinR
ChloramphenicolS
ClindamycinS
MacrolidesErythromycinR
AzithromycinR
ClarithromycinR
KetolideTelithromycinX1
TetracyclinesDoxycyclineX1
MinocyclineX1
GlycylcyclineTigecyclineS
DaptomycinX1
Glyco/LipoclycopeptidesVancomycinX1
TeicoplaninX1
TelavancinX1
Fusidic AcidX1
TrimethoprimX1
TMP-SMXX1
Urinary AgentsNitrofurantoinX1
FosfomycinX1
OtherRifampinX1
MetronidazoleS
Quinupristin dalfoppristinX1
LinezolidX1
ColistimethateX1

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

See Also

References

  1. Sanford Guide to Antimicrobial Therapy 2014
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