Chorea
Background
- Movement disorder
Clinical Features
- Involuntary worm-like movements
Differential Diagnosis
Autoimmune
- Sydenham's Chorea - due to acute Rheumatic Fever
- Lupus
- Oral Contraceptives [1]
- Chorea Gravidarum - usually in 1st trimester pregnancy [2]
Vascular
- Stroke
- Postpump chorea - in children after cardiac surgery
- Polycythemia vera
Metabolic Disorders
Drugs
- Illicit Drugs
- Dopamine Receptor Antagonists
- Metoclopramide (Reglan)
- Cimetidine
- Digoxin
- Isoniazid
- Verapamil
- Theophylline
Paraneoplastic
- Small-cell lung cancer
Evaluation
Management
Treat the underlying disorder
Disposition
- Consult Neurology if cause is unclear
See Also
References
- Miranda M, et al. Oral contraceptive induced chorea: another condition associated with anti-basal ganaglia antibodies. J Neurol Neurosurg Psychiatry 2004; 75(2): 327-328
- Bordelon YM, et al. Movement disorders in pregnancy. Semin Neurol 2007; 27(5):467-475
- Chang MH, et al. Non-ketotic hyperglycaemic chorea: a SPECT study. J Neurol neurosurg Psychiatry 1996; 60(4): 428-430
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