Calcium channel blockers
CF = coronary flow, ION = ionotropy, SA/AV = nodes
| Ca Blocker | BP/SVR | HR | SA/AV | CF | ION |
| Nifedipine | +++ | + | - | + | - |
| Diltiazem | ++ | - | + | + | - |
| Verapamil | + | -- | ++ | + | - |
| Bepiridil | +++ | (-) | min. | +++ | - |
| Amlodipine | +++ | + | + | ||
| Felodipine | + | + | |||
| Nicardipine | |||||
| Clevidipine |
Doses:
- Nifedipine
- 10-30 tid (Adalat CC: 30-90 qD)
- Diltiazem
- 60-120 TID (CD: 180-360 qD)
- Verapamil: 80- 120mg TID
- Bepiridil: 200-400mg QD
- Amlodipine: 2.5- 20mg (10) qD
- Nicardipine
- PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
- IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
- Clevidipine: 1-2 mg IV per hour
See Also
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