Bronchopulmonary dysplasia

Background

  • Chronic lung disease that develops in premature infants who require prolonged mechanical ventilation and/or supplementary oxygen, usually due to respiratory distress syndrome
  • Develops within first 4 weeks of life while infant still in NICU
  • Typically lung function improves with time, but many require long term O2 supplementation or other therapy

Clinical Features

  • May be asymptomatic until something (e.g. infection, respiratory irritant) triggers decompensation
  • SOB
  • Hypoxia
  • Increased respiratory secretions
  • Wheezing, crackles
  • +/- pulmonary hypertension
  • Poor feeding

Differential Diagnosis

Pediatric Wheezing

Evaluation

  • Typically not an ED diagnosis
  • Evaluate for precipitants of decompensation (e.g. infectious workup etc.)
  • CXR
    • Hyperinflation, low diaphragm, atelectasis, cystic changes

Management

  • Escalate chronic home therapies
  • Supplementary O2 and/or positive pressure ventilation as needed
  • Bronchodilators
  • Diuretics if euvolemic-hypervolemic
  • Treat decompensated pulmonary hypertension

Disposition

  • Low threshold to admit for acute respiratory symptoms

See Also


References

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