Aphthous stomatitis
Background
- Affects 20% of the normal population
- Unclear etiology. Common triggers: stress, hormonal changes, smoking, certain food such as coffee, chocolate.
- Resolve spontaneously in 10-14d
Clinical Features

Apthous ulcer of lip
- Involves the nonkeratinized epithelium (especially labial and buccal mucosa)
- Begins as erythematous macule that ulcerates and forms a central fibropurulent eschar
- Lesions measure from 2-3mm to several cm in diameter
Differential Diagnosis
Evaluation
- Clinical diagnosis
Management[1]
- Topical corticosteroids
- Betamethasone syrup OR
- Dexamethasone 0.01% elixir as mouth rinse OR
- Fluocinonide 0.05% gel applied topically to isolated lesions
- Biopsy to evaluate for malignancy or immune-mediated disease is recommended if lesion does not respond appropriately to steroids
Disposition
Discharge
See Also
References
- Tilliss TS, Mcdowell JD. Differential diagnosis: is it herpes or aphthous?. J Contemp Dent Pract. 2002;3(1):1-15.
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