Anaerobic bacteria
Background
- Origin - gut, mouth, head/neck (50% of chronic sinusitis), lung, female gu tract
- Cant grow unless culture specifically asked. 3% of bacteremia, <1% of cystitis
Organisms
- Bacteroides (GNR)
- Peptostreptococus (GPC)
- P. Acnes (GPR)
- Clostridium (GPR)
Anerobic Antibiogram
| Category | Organism | Actinomyces | Bacteroides fragilis | Prevotella melaninogenica | Clostridium difficile | Clostridium (not difficile) | Fusobacterium necrophorum | Peptostreptococcus sp. |
| Penicillins | Penicillin G | S | R | S | X2 | S | I | S |
| Penicillin V | I | I | R | X1 | S | I | S | |
| Anti-Staphylocccal Penicillins | Methicillin | R | R | R | X1 | X1 | X1 | S |
| Nafcillin/Oxacillin | R | R | R | X1 | X1 | X1 | S | |
| Cloxacillin/Diclox. | R | R | R | X1 | X1 | X1 | S | |
| Amino-Penicillins | AMP/Amox | S | R | S | X1 | S | S | S |
| Amox-Clav | S | S | S | X1 | S | S | S | |
| AMP-Sulb | S | S | S | X2 | S | S | S | |
| Anti-Pseudomonal Penicillins | Ticarcillin | X1 | R | S | X1 | S | X1 | S |
| Ticar-Clav | X1 | S | S | X1 | S | S | S | |
| Pip-Tazo | X1 | S | S | X1 | S | S | S | |
| Piperacillin | S | R | S | X2 | S | X1 | S | |
| Carbapenems | Doripenem | X1 | S | S | X2 | S | S | S |
| Ertapenem | S | S | S | X2 | S | S | S | |
| Imipenem | S | S | S | X2 | S | S | S | |
| Meropenem | X1 | S | S | X2 | S | S | S | |
| Aztreonam | R | R | R | R | R | X1 | R | |
| Fluroquinolones | Ciprofloxacin | R | R | R | R | I | X1 | I |
| Ofloxacin | I | R | I | X1 | I | X1 | I | |
| Pefloxacin | X1 | R | X1 | X1 | X1 | X1 | X1 | |
| Levofloxacin | X1 | R | S | R | S | X1 | S | |
| Moxifloxacin | S | I | S | R | I | I | S | |
| Gemifloxacin | X1 | R | X1 | X1 | X1 | X1 | X1 | |
| Gatifloxacin | S | I | S | R | S | X1 | S | |
| 1st G Cephalo | Cefazolin | X1 | R | X1 | X1 | X1 | X1 | X1 |
| 2nd G. Cephalo | Cefotetan | X1 | I | S | X1 | S | X1 | S |
| Cefoxitin | X1 | S | S | R | S | S | S | |
| Cefuroxime | X1 | R | S | X1 | S | X1 | S | |
| 3rd/4th G. Cephalo | Cefotaxime | X1 | R | S | R | S | X1 | S |
| Cefizoxime | S | I | S | R | S | X1 | S | |
| CefTRIAXone | S | R | I | X1 | S | X1 | S | |
| Ceftaroline | X1 | R | X1 | X1 | X1 | X1 | X1 | |
| CefTAZidime | X1 | R | S | X1 | S | X1 | S | |
| Cefepime | X1 | R | R | R | X1 | X1 | S | |
| Oral 1st G. Cephalo | Cefadroxil | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
| Cephalexin | X1 | R | X1 | X1 | X1 | X1 | S | |
| Oral 2nd G. Cephalo | Cefaclor/Loracarbef | X1 | R | S | X1 | X1 | X1 | S |
| Cefproxil | X1 | R | S | X1 | S | X1 | S | |
| Cefuroxime axetil | X1 | R | S | X1 | S | X1 | S | |
| Oral 3rd G. Cephalo | Cefixime | X1 | R | S | X1 | R | X1 | S |
| Ceftibuten | X1 | R | X1 | X1 | X1 | X1 | X1 | |
| Cefpodox/Cefdinir/Cefditoren | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
| Aminoglycosides | Gentamicin | R | R | R | R | X1 | R | R |
| Tobramycin | R | R | R | R | X1 | R | R | |
| Amikacin | R | R | R | R | X1 | R | R | |
| Chloramphenicol | X2 | X2 | S | I | S | S | S | |
| Clindamycin | S | I | S | X1 | I | S | S | |
| Macrolides | Erythromycin | S | R | X1 | X1 | I | R | I |
| Azithromycin | S | R | S | X1 | S | R | S | |
| Clarithromycin | S | R | S | X1 | S | R | I | |
| Ketolide | Telithromycin | X1 | X1 | X1 | X1 | X1 | X1 | S |
| Tetracyclines | Doxycycline | S | I | S | X1 | S | X1 | S |
| Minocycline | S | I | S | X1 | S | X1 | S | |
| Glycylcycline | Tigecycline | X1 | S | S | X1 | S | S | S |
| Daptomycin | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
| Glyco/Lipoclycopeptides | Vancomycin | S | R | R | S | S | X1 | S |
| Teicoplanin | X1 | X1 | X1 | S | S | X1 | S | |
| Telavancin | S | R | R | S | S | X1 | S | |
| Fusidic Acid | S | X1 | S | X1 | S | X1 | S | |
| Trimethoprim | X1 | X2 | X1 | X1 | X1 | X1 | X1 | |
| TMP-SMX | X1 | R | X1 | X1 | X1 | X1 | X1 | |
| Urinary Agents | Nitrofurantoin | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
| Fosfomycin | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
| Other | Rifampin | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
| Metronidazole | R | S | S | S | S+ | S | I | |
| Quinupristin dalfoppristin | X1 | X1 | S | I | X2 | X1 | X1 | |
| Linezolid | X1 | I | X1 | I | X2 | X1 | S | |
| Colistimethate | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
Table Overview
See Also
References
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