Alpha-2 agonists

Background
  • Central α agonists lower blood pressure by stimulating α-receptors in the brain which causes peripheral vasodilation

Medications
  • clonidine
  • guanabenz
  • guanfacine
  • methyldopa
  • moxonidine
  • Xylazine (veterinary med, drug of abuse)

Adverse effects
  • sedation
  • drying of the nasal mucosa
  • rebound hypertension

See Also
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